Chemistry E-Notebook
E-Notebook provides a smooth, well-organized interface designed to replace paper laboratory notebooks. With E-notebook, users can easily insert content from Word, Excel, PowerPoint, Acrobat PDF, ChemDraw and structured data in lists and tables. Forms are configured with any combination of these. Oracle or SQL support allows organizations to share data, as well as maintain rigorous security and efficient archiving. With E-Notebook, users get the flexibility of a shared drive with the compliance and search benefits of an Oracle database.
E-Notebook has been developed over the last 10 years in close collaboration with many of the world’s top research and development organizations. This development has been facilitated by detailed interactions with leading compliance and intellectual property experts as well as some of the best system architects in R&D. If your organization wants an enterprise electronic laboratory solution, you need look no further.
Under the R&D value chain, chemistry can be further divided into three separate stages: synthetic chemistry (research/discovery), analytical chemistry (pre-clinical) and process chemistry (development). The flexibility and configurability of E-Notebook enables a successful data repository, analysis, sharing, reporting, and searching efficiently and paper-free.
Synthetic Chemistry
Synthetic Chemists take advantage of many features tied into a smooth interface within CambridgeSoft’s Enterprise E-Notebook. Reactions are drawn with in-place editing; a stoichiometry grid dynamically fills with the formulas, molecular weights, and chemical names. Reagents can also be imported from other systems, such as available chemicals from the ChemACX database or Registration system. CombiChem is one important aspect of library generation for Synthetic Chemists. For some, E-Notebook serves as the complete CombiChem solution, taking advantage of features such as the enumeration of products from a virtual library on a flexible plate layout, a multiple reaction site checker, and multiple step parallel synthesis. Others simply import a list of compounds from an external source or SDFile so that they can record and calculate data on a library-wide stoichiometric table.
Analytical Chemistry
E-Notebook serves as a repository for analytical data, and it also acts as a communication portal with which scientists and analysts communicate with each other. Scientists can create and send service requests directly to an analyst with the click of a button. Paper is eliminated: when results are obtained, the analyst can send the images and chromatograms directly back to the scientist's E-Notebook.
Process Chemistry
The objective of process research is to identify efficient processes for the synthesis of active pharmaceutical agents at the scale required for clinical trials and commercial use. It is necessary to provide precise descriptions of these processes so that they can be executed by different groups in different locations. It is also required that such processes be compliant with Good Laboratory Practices (GLP), Good Manufacturing Processes (GMP) and the FDA's 21 CFR Part 11 regulation. E-Notebook's process chemistry modules are designed to support these dual workflow and regulatory compliance needs of process chemists.
