Press Release

COLORADO SPRINGS, CO & CAMBRIDGE, MA — 4 April 2008 — Stewart Computational Chemistry, provider of MOPAC®, the leading semi-empirical quantum chemistry program, and CambridgeSoft Corporation, a leading provider of desktop and enterprise-class software for the pharmaceutical and biotechnology industries, announced today that that they have formed an alliance to ensure compatibility between MOPAC2007™ and the latest versions of the ChemBioOffice® application suite, including the ChemBio3D® modeling and visualization application.

News of the partnership follows Stewart Computational Chemistry’s recent launch of MOPAC2007, a semiempirical quantum chemistry software package for the prediction of chemical properties and modeling of chemical reactions. It is used by chemists and biochemists for both research and teaching. MOPAC2007 is a completely updated and rewritten version based on the public domain MOPAC 6 with many bug fixes and several major enhancements added.

Through the alliance, CambridgeSoft will offer MOPAC2007 as an add-on to its leading desktop modeling and visualization program ChemBio3D. ChemBio3D allows scientists to visualize detailed 3D complexes structures using open GL graphics and stereo hardware. Other important features include the ability to build small molecules using the ChemDraw interface, display and analyze hydrogen bonds and partial surfaces, and perform basic molecular modeling computations such as alignment, dihedral driver MM2 experiments, Molecular Mechanics with support for MMFF94.and Dynamics.

"We are pleased to be working together with Stewart Computational Computing to provide the leading semi-empirical computation engine of MOPAC2007 to our ChemBio3D users," said Michael G. Tomasic, President and CEO of CambridgeSoft. "With this agreement, we are ensuring that our customers benefit by being able to integrate the CambridgeSoft tools of their choice into existing best-of-breed computational engines.” Dr Stewart added "CambridgeSoft 's easy-to-use graphical interface will provide access to the new capabilities in MOPAC2007 for many more chemists and biochemists than would otherwise be practical."

About Stewart Computational Chemistry

Stewart Computational Chemistry is engaged in the research and development of semiempirical quantum chemistry methods within the MOPAC framework. Led by the original author of MOPAC, James J. P. Stewart, Stewart Computational Chemistry's mission is to continue to enhance MOPAC as a state-of-the-art quantum chemistry tool for solving practical chemistry and biochemistry problems, while keeping MOPAC freely available to academics. For technical information about MOPAC contact SCC at www.openmopac.net. For sales information please contact CAChe Research at www.cacheresearch.com/mopac.html or call +1 503 830 2772.

About CambridgeSoft Corporation

CambridgeSoft develops and markets life science enterprise solutions for pharmaceutical, biotechnology, chemical companies and academic research organizations. Software products include enterprise, workgroup and desktop, versions of Chem & Bio Office, including Chem & Bio Draw, with knowledge management, chemical and biological informatics, and scientific database solutions. Web sites include ChemFinder.Com and ChemBioNews.Com for indexed database content and news, and SciStore.Com for e-commerce. For information about CambridgeSoft products, services, and sales worldwide, please visit www.cambridgesoft.com, or call 1 617 588-9300 in America, in Europe call 00 800 875 20000, or in Japan call 0120-146-700.

Contacts:

CAChe Research LLC
(for Stewart Computational Chemistry)
David A. Gallagher
(503) 830 2772

CambridgeSoft Corporation
Jerald Baronofsky
Director, Marketing and Sales
(617) 588-9347